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Tuberculosis - TB

Duncan MacDonald     
Jakarta   23  March   2006      

What! – Me Worried?

Are you worried about Bird Flu? Over the past few months I have lost count of the seminars, luncheons, briefings and educational sessions I've attended dealing with the potential danger of Bird Flu.

Chicken Little There is no doubt a lot of birds are dying from Bird Flu. More than 140 million chickens and ducks across Asia have been killed or culled since 2003.

If I was a duck I'd be worried.

But have you actually sat back and considered how many people have been killed so far by Bird Flu?

   I checked !!    Up until 16-Mar-2010, the number of people world-wide who have died from the H5N1 virus totals just 289 [1]
That's right - two hundred & eighty nine. And 136 have died in Indonesia [2]

Health experts say the virus is difficult for humans to catch, but they fear it could mutate and set off a flu pandemic that could kill millions of people world-wide. In case you didn't know (and the WHO [World Health Organisation] people keep forgetting to tell you this) all flu viruses come from birds. They all mutate, which is why last year's flu shot won't work this year - it has mutated !

If you want to worry, read our article on the 1918 Spanish Flu, which killed between 50 million and 100 million people in 25 weeks.

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If you really truly want to worry - read on . . .

What do you know about the second most infectious killing disease in the world (HIV / AIDS leads with 3 million people per year and malaria is 3rd with 1 million).

This disease kills 2 million people each year world-wide. It kills 150,000 Indonesian each year - every year. Ironically it is entirely preventable. [3] examining for TB

I am talking about TUBERCULOSIS.
Remember all the seminars, TV documentaries and magazine articles you've seen about bird flu - which has killed, remember, 136 Indonesians since 2003.

Just to put things in perspective, TB has killed approximately 1,050,000 Indonesians between 2003 and 2010. That's over 400 each day

How many seminars, TV documentaries and magazine articles have you read lately about TB ? Not very many I'll warrant.

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Why is this so?

One theory I'm hearing from my medical friends, tuberculosis doesn't get much air play because the great majority of the victims are in developing countries. And it's been around forever. On the other hand, WHO is getting humungous additional funding by pushing the bird flu scare.

I don't believe that for one minute. . . . . Well, not more than a couple of minutes anyway.

Should you be worried about TB?
First let's have a quick look at Tuberculosis 101.

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History of TB

TB has been present in humans since antiquity. The origins of the disease coincide with the first domestication of cattle. Skeletal remains show prehistoric humans (4,000 BC) had TB.

Around 460 BC, Hippocrates identified Phthisis (a Greek term for consumption) as the most widespread Robert Kochdisease of the times, which was almost always fatal. [4]

German physician Robert Koch described the bacillus tuberculosis, Mycobacterium tuberculosis on 24 March 1882. He received the Nobel Prize in medicine in 1905 for this discovery. However Koch did not believe bovine (cattle) and human tuberculosis were similar, which held back the recognition of infected milk as a source of infection. Later this source was eliminated by pasteurisation.

The cause of tuberculosis (or consumption so named because sufferers appeared to be consumed by the disease from within, or Phthisis), Mycobacterium tuberculosis (MTB), is a slow growing aerobic bacterium that divides every 16 to 20 hours. This is extremely slow compared with other bacteria (E.coli is one of the fastest dividing approximately every 20 minutes).

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Infection and Transmission

Tuberculosis is a contagious disease. Like the common cold, it spreads through the air when infectious people cough, sneeze, talk or spit. A person only needs to inhale a small number of the TB germs known as bacilli, to become infected. [5]

TB is spread through the air. People cannot get infected with TB bacteria through handshakes, sitting on toilet seats or sharing eating utensils with someone who has TB. (Although you may contact bird flu by shaking [hands?], sharing toilet seats or cooking utensils with an H5N1 infected bird).

You do the math - While only 10% of TB infection progresses to TB disease, if untreated, the death rate is 51%.

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TB patient

Symptoms

Symptoms of active TB includes; weakness, weight loss, fever, no appetite, chills, and sweating at night. If active TB disease is in the lungs (pulmonary TB) the symptoms may include a bad cough, pain in the chest and coughing up blood.

HIV and TB form a lethal combination, each speeding the other's progress. HIV weakens the immune system. An HIV-positive person infected with TB is many times more likely to become sick with TB disease than someone who infected with TB who is HIV-negative

Drug-resistant TB Sixty years ago there were no medicines to cure TB. Now strains that are resistant to a single drug have been documented in every country surveyed, including Indonesia.

Poorly supervised or incomplete treatment is worse than no treatment at all. The patient may remain infectious and their lungs develop resistance to anti-TB medicines. People they infect will have the same drug resistant strain. [6]
doc checking x-ray Indonesia ranks 3rd on the list of 22 high-burden tuberculosis countries in the world – after China and India. [7]

The head of the TB elimination program in Lampung, Dr. Elvi Suryati, said a health office survey found that at least 10 people on virtually every block in one sub-district in the provincial capital Bandarlampung had tuberculosis. Seventy-five percent of people who developed active TB and eventually died of the disease were in their productive years, ranging in age from 15 to 49. [8]

TB has been classified as endemic in Bandarlampung, with three sub-districts being most susceptible to the spread of the disease. The survey found that 10 out of 11 people in each sub-district are believed to have contracted TB. This is the highest figure found throughout Indonesia. [9]

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Effective TB control – DOTS

The DOTS strategy (Directly observed therapy), introduced in 1991, prevents new infections by curing infectious patients. A six month supply of drugs for treatment under the DOTS strategy costs as little as US$10 per patient.


TB in Art, Literature, History & Film Edgar Allen Poe

Many historically prominent people developed or died from tuburculosis, often in the prime of their productive period.

The pale haunted appearance of tuberculosis sufferers was fashionable at times, and has been seen as an influence on the works of Edgar Allen Poe who lost loved ones to this disease.

It is tragic that this disease has not been brought under control, because I am living proof that TB can be effectively treated and cured" said Nobel laureate Archbishop Desmond Tutu, who along with former South African President Nelson Mandela is a survivor of TB. [10]

English romantic poet John Keats (1795-1921) and some of his family were taken by TB.

Frederic Chopin died of consumption in 1849. Doc Holliday

Famous dentist, gambler and gunslinger John "Doc" Holliday suffered from tuberculosis until his death in 1887. Doc and his bloody cough were portrayed by Val Kilmer in the 1993 film Tombstone.

Legendary father of country music, Jimmy Rodgers (1897 - 1933) wrote the song T.B. Blues. He died of the disease days after a New York city recording session.
Geta Garbo
Franz Kafka (1883-1924) a German-language novelist, made famous by his novel The Metamorphosis, died from TB.

In the period picture Camille, MGM 1936, consort Greta Garbo (Camille) tragically contacts consumption and dies in Robert Taylor's arms.

In Finding Neverland, Kate Winslet's character suffers and dies from tuberculosis.

In the novel The Constant Gardener by John Le Carre as well as in the award winning movie, the plot largely revolves around TB drugs being tested on unwitting subjects in Africa and dire predictions of a global pandemic if a drug-resistant form of the disease appears.

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A word to the wise

Remember that 10 out of 11 people near Lampung have contracted TB. There is a high rate of TB in rural areas in Indonesia. Your pembantu (maid) most likely came from a kampung. Have your domestic staff tested for TB. Your children are most vulnerable to TB.

Laurel with Daisy

PERSONAL FOOTNOTE - from the Webmaster

My grand-mother, on my Mother's side, Imelda Mary White (Daisy), died of tuberculosis aged 30, in 1925.

She is pictured here with my Mother, Laurel, in 1919.
Laurel died of cancer, aged 40, in 1957.

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      Statins                         Tennis ElbowNext
Reviewed    16  October   2017

Contents

What - Me Worried ?

If you really want to worry - read on

Why is this so ?

History of TB

Infection & Transmission

Symptoms

Effective TB control - DOTS

TB in Art, Literature, History & Film

A word to the Wise

Personal Footnote - from the Webmaster

 

 

Reference
1. World Health Organisation, 14-Mar-2010

2. World Health Organisation, 6-May-2010

3. The Global Fund to fight AIDS, Tuberculosis & Malaria, 2006

4. US Embassy Jakarta, Environment Science & Technology and Health Highlights, Feb & Mar-2005

5. World Health Organisation, Fact sheet Nº104, revised Apl-2005

6. http://www.who.int/mediacentre /20-03-2006

7. USAID Infectious Diseases - Indonesia

8. Dr Elvi Suryati, Head of the TB elimination program in Lampung

9. Dr Elvi Suryati

10. Sudan Tribune 26-Aug-2005